Narcolepsy Clinical Trials in Michigan

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Struggling with Sudden Sleep Episodes?

Participate in Type 1 Narcolepsy Clinical Trials Today!

Narcolepsy with cataplexy is a chronic sleep disorder that disrupts life with overwhelming daytime sleepiness and sudden episodes of muscle weakness triggered by intense emotions. These symptoms affect work, relationships, and daily routines. If you are living with narcolepsy, you may feel isolated or frustrated by the lack of effective treatments.

Revive Research Institute is currently recruiting participants for Type 1 Narcolepsy Clinical Trials in Michigan, aimed at exploring innovative treatment options. These studies focus on the safety and efficacy of investigational narcolepsy treatment drugs, providing hope for better symptom management and improved quality of life for those living with this condition.

Eligibility Criteria

Diagnosed with type 1 narcolepsy or narcolepsy with cataplexy
18 to 70 years of age
Has a BMI within the range 18 to 40 kg/m²

Our group of licensed and certified physicians will be keeping track of the patient’s progress throughout the study and will address any concerns or queries that arise regarding the research trial.

*Additional criteria may apply.

Participation in the Type 1 Narcolepsy Clinical Trial is completely free of cost and requires no insurance. Eligible participants receive study-related care, including the investigational drug, at no cost. Compensation may also be provided for time and travel.

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About Type 1 Narcolepsy Clinical Trials

We are conducting Type 1 Narcolepsy Clinical Trials in Michigan to evaluate the safety, efficacy, and tolerability of investigational treatments for narcolepsy with cataplexy. These trials aim to explore better options for the treatment of narcolepsy by potentially managing symptoms like excessive daytime sleepiness, disrupted sleep cycles, and cataplexy (sudden loss of muscle tone while awake, often triggered by emotions).

Most of our studies are double-blind and placebo-controlled, ensuring unbiased and reliable results. Participants may receive either the investigational drug or a placebo (without the active ingredient). However, the study doctor will have access to this information to ensure participant safety in case of adverse events.

Clinical trials are a vital part of advancing medical science. They help researchers and physicians understand how new treatments perform in real-world settings while adhering to strict ethical guidelines to prioritize participant safety and well-being.

*All study procedures and study-related treatment including the investigational drug is free of cost to you and insurance is not required to participate.

*The study doctor and team will take you through every step of the clinical trial before you decide to participate and will answer any questions you have about the study treatment.

The Impact of Narcolepsy Clinical Trials

Narcolepsy is a life-altering condition that demands innovative solutions. Clinical trials like those conducted at Revive Research Institute aim to address unmet medical needs, exploring therapies that could significantly improve the lives of individuals living with narcolepsy.

Preliminary studies on investigational treatment for narcolepsy have shown promising results. For example, medications targeting hypocretin pathways or enhancing REM sleep stability have demonstrated the potential to reduce excessive daytime sleepiness and cataplexy episodes.

According to Psychology Today, about 70% of people with narcolepsy experience cataplexy, yet fewer than half receive a timely diagnosis. This delay underscores the importance of research to improve diagnostic tools and therapeutic options.

If you or a loved one are living with narcolepsy, don’t wait. Take the first step toward better symptom management and explore the possibilities of cutting-edge treatments. Enroll in a Type 1 Narcolepsy Clinical Trial in Michigan today!

Condition

Narcolepsy with Cataplexy

Length of Study

Approx. 6 months

No. of Study Visits:

Approx. 8–10

Understanding Narcolepsy and Cataplexy

Narcolepsy is dyssomnia, a category of sleep disorders characterized by disruptions in the timing, quality, or quantity of sleep. It affects approximately 1 in 2,000 people in the U.S., according to the National Institute of Neurological Disorders and Stroke (NINDS). Narcolepsy often begins in childhood or adolescence, although it can be diagnosed at any age.

Symptoms of Narcolepsy with Cataplexy:

Excessive Daytime Sleepiness (EDS): A hallmark symptom, characterized by an uncontrollable urge to sleep, even during activities like talking or eating.
Cataplexy: Sudden, brief episodes of muscle weakness triggered by strong emotions such as laughter, surprise, or anger.
Sleep Paralysis: Temporary inability to move or speak while waking up or falling asleep.
Hallucinations: Vivid, dream-like experiences that occur while falling asleep (hypnagogic) or waking up (hypnopompic).
Disrupted Nighttime Sleep: Frequent awakenings, vivid dreams, and restless sleep patterns.

Causes of Narcolepsy

Narcolepsy is often linked to a deficiency of hypocretin (orexin), a brain chemical that regulates wakefulness and REM sleep. In individuals with narcolepsy, the immune system may mistakenly attack hypocretin-producing neurons, leading to this deficiency.

Genetics also play a role, as narcolepsy is more common among individuals with a specific variation of the HLA-DQB1 gene. However, environmental factors like infections or stress may also trigger the onset of symptoms.

Why Participate in a Clinical Trial?

Participating in clinical trials offers numerous benefits:

Access to Potential Treatment Options: Participants receive investigational therapies not yet available to the public.
Expert Medical Care: Regular monitoring by a team of experienced medical professionals ensures your safety and well-being.
Advancing Science: By participating, you contribute to developing better treatment options for future generations.
No Cost: All study-related care, including tests and medication, is provided at no cost.
Compensation: Participants may receive financial compensation for time and travel expenses.

Clinical trials are hope for those who have exhausted conventional treatment options. They provide an opportunity to explore alternative therapies and actively participate in advancing medical research.

What to Expect – Step by Step

Pre-Screening: Complete an online form or call our research team. A representative will assess your initial eligibility through a brief pre-screening questionnaire.
Informed Consent: If pre-qualified, you will receive an Informed Consent Form (ICF) outlining the study’s details, potential risks, and benefits. You must sign this form before participating.
Screening Visit: Attend a screening appointment where study doctors will perform tests and assessments to confirm your eligibility.
Study Participation: Once enrolled, you will attend approximately 8–10 study visits over a six-month period. During these visits, your symptoms, overall health, and response to the investigational treatment for narcolepsy (being studied) will be closely monitored.

Addressing Common Questions

What is Narcolepsy with Cataplexy?

Narcolepsy with cataplexy is a chronic neurological condition that affects the brain’s ability to regulate sleep-wake cycles. It is characterized by excessive daytime sleepiness and episodes of sudden muscle weakness triggered by emotions.

Do I have to pay to participate in Narcolepsy Clinical Trials in Michigan?

No, participation is entirely free. All study-related care, tests, and the investigational drug are provided at no cost.

Will I be compensated?

Yes, participants may receive financial compensation for their time and travel. Specific details will be shared during the informed consent process.

Are clinical trials safe?

Clinical trials follow strict ethical and regulatory guidelines to ensure participant safety. Every study is reviewed and approved by an independent ethics committee, and participants are monitored closely by medical professionals throughout the trial.

Type 1 Narcolepsy Clinical Trials